Mitochondria in nerve cells have been shown to play a key role in nerve functioning.  Many recent studies are implicating poor functioning mitochondria with presentations of peripheral neuropathy and even with the associated neuropathy pain. 

Mitochondria are better understood as the energy supplier for cells, and also assists in the cellular functions stimulating cell growth and signaling cell death.  These important functions allow nerve cells and other cells of the body to function normally.  When the pathway to mitochondrial production are disrupted or function poorly, the mitochnodria will be malformed or depleted and cause many cell abnormalities, including neuropathy. 

A key nutrient for this pathway is vitamin B-9 (Folate or folic acid as it is known in supplement form).  Although the foods in the United States often have B-9 as an additive, many with neuropathy may have reasons why they have insufficient folate in their blood stream.  Folic acid supplementation can therefore lead to improved functioning of the nerves through assisting with mitochondrial production.  

Recommended Folic Acid (Folate) Dosage

Folic acid should be supplemented as follows:

  • Adults (> 18):  600 - 700 micrograms daily.
  • Children: Should be carefully monitored by a physician as lower dosages can be tolerated.
Brandt R Gibson, DPM
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Podiatrist, Neuropathy Doctor, Father of 11 and Founder of Mountain West Foot & Ankle Institute