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New Gene Identified That May Lead To Neuropathy

Brandt R Gibson, DPM
Podiatrist, Neuropathy Doctor, Father of 11 and Founder of Mountain West Foot & Ankle Institute
Posted on Oct 04, 2011
In many recent studies, mitochondria in the nerve cells have been implicated with causing some forms of peripheral neuropathy.  In fact, some studies for treatments have been looking at mitochondria as the possible pathway to improve neuropathy symptoms. 

With this background, a recent study by Dr Patrick Stover and colleagues at Cornell University may have implications for neuropathy treatment.  This study identified a gene that participates in the replication of mitochondria, and may indicate a gene that can cause peripheral neuropathy.  In this study, published Aug. 26 in the Proceedings of the National Academy of Sciences,  identified the gene as shown:

A newly identified human gene, DHFRL1, (nucleus in blue) may be a key to some forms of neuropathy. (Credit: Stover lab)

A newly identified human gene, DHFRL1, (nucleus in blue) may be a key to some forms of neuropathy. (Credit: Stover lab)

 

How is this finding important?   The process in the body that DHFRL1 participates in to produce mitochondria is facilitated by folate (or folic acid) that can be supplemented.   Another confirmation that B-9 (Folate or Folic Acid) can help improve the nerve functioning in neuropathy.

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